Important: We cannot accept online consultation bookings at this timeDue to a problem with our payment system, we cannot accept online consultation bookings at this time. We plan to resume around Sat, Nov 14, but we cannot guarantee this date. We will let you know on this page and on our official LINE when we resume. If you already have a booking, we will contact you individually by LINE or email. We sincerely apologize for the inconvenience.
Open our official LINE

Our philosophy

Preventive medicine, at a price you can keep up with.

Obesity is a root cause of lifestyle diseases such as diabetes, high blood pressure and dyslipidemia, and it is also known to raise the risk of depression. Losing weight is not only about appearance; it is medical care that prevents future illness.

We also believe that maintaining the body shape you consider ideal helps you live a life that is truly your own.

In Japan, GLP-1 receptor agonists for obesity disease are covered by public health insurance. However, the requirements for insurance use are strict, and in practice only a small fraction of people can start treatment under insurance.

We believe that, even in self-pay care, these medicines can be used safely once a physician has properly assessed whether they are appropriate. That is why we never skip the consultation, and we decline to prescribe when the treatment is not appropriate.

To spread preventive medicine, we make it possible to start at a price you can comfortably continue. That is our philosophy.

New here?

Not sure? Watch first. We show you how to book, screen by screen

A walkthrough of the new booking site, using the actual screens. Watch before you book and it goes smoothly.

The delivery address cannot be changed after payment

When you pay, please enter an address where you can reliably receive your package.

Cancellation and refunds

We contact you through LINE. Please add our official LINE account before you book

There have been a few patients we were simply unable to reach, and we could not send them their medication. Emails and notifications from other apps get buried among other alerts, so many people never notice them. Tracking numbers and any discussion about where to receive your parcel are sent through our official LINE account. Every one of these problems can be prevented just by adding us as a friend. We only contact you about your own booking and your own medication. We never send advertising or mass broadcasts. If you no longer need us, you are welcome to block the account at any time.

当院からお送りするのは、患者様のご予約とお薬に関するご連絡だけです。宣伝や一斉配信は一切いたしません。ご不要になりましたら、いつでもブロックしてくださって構いません。

💬Add our official LINE account
10 clinics in Tokyo · Genuine Japanese supply

Mounjaro 2.5mg
from ¥8,000 a month.

We are a cosmetic dermatology group with 10 physical clinics in Tokyo. The figure below is the real total, shipping included - nothing else is added. Collect your medication at your hotel or a Yamato Transport office.

Mounjaro 2.5mg x 4 pens 1 month, total¥9,215 3 months: ¥25,215 total (¥8,405 per month)
Medication, consultation and shipping — nothing else to pay
¥8,000 by card + ¥1,215 shipping paid on delivery (Kanto)
Shipping varies by region. No first-visit or follow-up consultation fees.
✓No consultation fee ✓Consultation about 5 days before delivery ✓Hotel or Yamato pickup ✓Collect with your passport

The booking site is in Japanese only. If anything is unclear, contact us on our official LINE

3-min sign up / Pay after the consultation / Free cancel ※We have a new booking site; the previous one can no longer be used. After booking, please send “I have booked” and your name to our official LINE

Hello, I'm your doctor!
Attending doctor character
LINE
Everything reaches you on LINE

Your tracking number and any discussion about where to collect your parcel happen on our official LINE account.

Please send questions and requests to our official LINE account as well - that is where we reply fastest.

💬Add us on LINE
Before you book

Bookings are taken on our booking site. The booking site is in Japanese only; if anything is unclear, contact us on our official LINE. If the booking site or the payment page will not open from overseas (403 error), connect to Japan via a VPN first and then open it.
Please book about 5 days before the day you want to receive your medication. If you book a week or more earlier, we will ask you to book again.

10,000+
Mounjaro prescriptions
★4.6
~800 Google reviews (Shinjuku)
10 clinics
We also see patients in person for consultations, in Shinjuku Kabukicho and elsewhere
*"4.6★ / approx. 800 reviews" per Google (Shinjuku clinic, as of August 2026). The reviews are ratings written by third parties on Google. Prescription figures, the number of people seen and the number of clinics are our clinic's own totals.
PRICE

Mounjaro Pricing

Prices changed on September 1, 2026

The multi-month discount has been discontinued and the price per month is now the same for every duration. The 2.5 mg dose is now less expensive. The new prices are shown below.

All-inclusive totals. With a multi-month prescription you only need one consultation, and shipping is charged only once.
Initial and follow-up fees are ¥0. Prices below are totals including cool delivery (¥1,215), and all listed prices include consumption tax. Shipping is paid on delivery, so your card is charged for the medication only (no fee).

The Mounjaro Atheos pens we dispense (2.5–15mg). Each dose has its own colour.+
Mounjaro Atheos, six doses
Plan
Total (Drug+Ship¥1,215) *shipping paid on delivery
Savings
1 Month
4 pens / 2.5mg×4
¥9,215
Drug ¥8,000 + Ship ¥1,215
―
2 Months
8 pens / 2.5mg×8
¥17,215
¥8,607/mo equiv.
Save ¥1,215
3 MonthsBest Value
12 pens / 2.5mg×12
¥25,215
¥8,405/mo equiv.
Save ¥2,430
Your payment is split into two parts
Your credit card is charged for the medication only (no fee).
Shipping (from ¥1,215) is paid on delivery. Pay the driver, or at the Yamato office counter. Cash, contactless card, transport IC cards (Suica etc.) and QR payments such as PayPay are all accepted (cards are contactless only).
Hotel deliveries are also paid on delivery. If you receive it yourself you can pay by cash, contactless card or PayPay. If the front desk accepts it for you, please leave cash for the shipping fee with them.
Listed prices include Japanese consumption tax. The totals in the price table already cover the medication and cool-delivery shipping; nothing else is charged. Shipping varies by region.
Cancellation and termination fees are both ¥0. There is no ongoing commitment, and you may stop at any time. We do not deliver on a recurring schedule. A prescription for just one month (4 pens) is perfectly fine. There is no auto-renewal, and booking again is entirely up to you.
View the price list (PDF - 4 to 12 months too)

Every dose and every plan length, with the all-in total on a single page. Plans of 4 months and longer - up to 12 - are not in the table above, but they are all listed here, including the oral medications.

For a prescription of 3 months or more

The price table above covers up to 3 months. Prices from 4 months through 12 months are listed in the PDF price list. At 3 months or more, the medication cost per month stays the same — ¥8,000 a month for 2.5mg. It still takes only one consultation and one delivery.

We take the medication out of its outer cartons and deliver everything in a single cool box. We cannot deliver it in the outer carton, and we cannot accommodate requests for a particular box size. We send a prescription certificate free of charge to everyone who receives a prescription, without your having to ask for it. It is a document written in both English and Japanese, and you can present it at customs.

※Totals are the medication cost + cool-delivery shipping (¥1,215, reference price within Kanto). Shipping varies by region. ※A multi-month prescription (2 or 3 months) is prescribed in a single consultation and sent in a single delivery. ※Savings are shown in comparison with a 1-month prescription repeated n times. ※Shipping is paid on delivery. Your card is charged for the medication cost only (no fee); please pay the driver for shipping when your parcel arrives. ※All listed prices include consumption tax.
※The medication cost per month is the same for every duration. However, shipping is charged only once, so you save ¥1,215 on a 2-month prescription and ¥2,430 on a 3-month one.
※Prices effective September 1, 2026. So that patients who prefer to start one month at a time are not penalised, we have discontinued the multi-month discount and set the same price per month for everyone. Self-pay care (not covered by insurance). Individual results vary.
※Payment is by VISA or Mastercard credit card only. Cards issued outside Japan can be used. JCB, American Express and Diners cards, and debit, check and prepaid cards, cannot be used. Please also check your credit limit and expiry date. If your payment does not go through, contact us on our official LINE.

Oral medication prices

For those who would rather not inject. Treatment with oral medication alone is possible.

Rybelsus (semaglutide, oral - one tablet daily)

Term3mg7mg14mg
1 Month¥10,000¥15,000¥22,000
2 Months¥18,000¥28,000¥42,000
3 Months¥25,000¥40,000¥60,000
4 months¥33,000¥53,000¥80,000
5 months¥41,000¥66,000¥100,000
6 months¥49,000¥79,000¥120,000

3mg is ¥5,000 for your first month only

Dapagliflozin (SGLT2 inhibitor, oral - one tablet daily)

Plan5mg10mg
1 month¥3,980¥4,980
2 months¥6,960¥8,960
3 months¥8,940¥11,940
The dapagliflozin 10mg tablets we dispense. Sourced through official domestic distribution.+
PTP sheet of dapagliflozin 10mg tablets

On the 3-month plan that works out at ¥2,980/month for 5mg and ¥3,980/month for 10mg. First-time patients start on 5mg.

Order it together with Mounjaro and the only extra cost is the medication itself. Shipping is charged once, and everything ships in the same box. For ¥3,980 more per month you work on both fronts at once.

A generic of Forxiga, listed on Japan's national drug price list in December 2025. We use only domestically distributed genuine supply. The generic is approved for type 2 diabetes only - it does not carry the chronic heart failure, chronic kidney disease or type 1 diabetes indications that the originator Forxiga has.

Other oral medicines

Metformin 500mg, 100 tablets¥4,000
Sanorex, 30 days¥15,000

All figures above are for the medication itself. Cool delivery from ¥1,215 (60-size, paid on delivery, Kanto reference) applies separately. We also take orders for oral medication on its own. If you order it together with Mounjaro, everything ships in one box, so you pay shipping only once. SaNorex is prescribed only after careful assessment. All prices include consumption tax.

SIMULATOR

Price Simulator

Pick your dose, plan, optional oral medication and delivery area to see the full total right away.

Total¥9,215
per month ¥9,215

※Medication is charged to your card (no fee). Shipping is paid on delivery - by cash, contactless card, transport IC card or QR payment such as PayPay.

Pharmacist characterExplained by our pharmacist

Available Medications

Doctors prescribe the optimal medication based on consultation, constitution, and goals.

Injectable / Once Weekly

Mounjaro

Tirzepatide / GIP・GLP-1 Receptor Agonist

The latest injectable acting on two hormone receptors at once. Once-weekly self-injection, stepping up 2.5 → 5 → 7.5 mg.

From ¥8,000 / month (2.5mg×4)
Oral Medication / Daily

Dapagliflozin

SGLT2 inhibitor / generic of Forxiga

Flushes excess sugar out through urine. One tablet daily. Works synergistically alongside Mounjaro.

¥3,980 / 30 days (5mg)
Oral Medication / Daily

Metformin

Biguanide / Oral

A long-established oral medicine with a strong safety record. It curbs glucose absorption and hepatic production, helping regulate metabolism. Can be shipped together.

¥4,000 / 100 tablets (500mg)
Oral / Daily

Rybelsus

Semaglutide / GLP-1 (Oral)

An oral GLP-1 for those who dislike injections. Suppresses appetite. One tablet daily.

From ¥5,000 first time / 30 days (3mg)
Oral / Short-term

Sanorex

Mazindol / Appetite Suppressant

A short-term appetite suppressant acting on the appetite center. The doctor carefully assesses suitability.

¥15,000 / 30 days
Discontinued

Wegovy

Semaglutide / GLP-1 Receptor Agonist

Currently not available at our clinic.

―

Injectable (Mounjaro)

Cool delivery (size 60) from ¥1,215 (Kanto)
Kanto ¥1,215 / N.Tohoku・Kansai ¥1,335 / Chugoku・Shikoku ¥1,465 / Hokkaido・Kyushu・Okinawa ¥1,735 (COD)

Oral Medication

Packed with the injectables No extra shipping charge
Multiple oral medications ship together in the same box

Payment fee

¥0 (none)
Your card is charged for the medication only

HOW IT WORKS

How It Works

All on your phone. Book and consult while you are in Japan.

From booking to done - only three things to do
  1. Register on our booking site, choose a date and time, and answer the questionnaire that follows. Please book about five days before the day you want to receive your medication.
  2. After booking, add our official LINE and send us “I have booked” with your name. If we do not hear from you on LINE by your booking time, your booking will be cancelled.
  3. After your consultation, pay through the payment link we email you (we also post the URL on LINE). You enter your delivery address and card details on the payment page.
The booking site and the payment page are in Japanese only. The clinic name shows as "UBCLINIC 新宿東口" (Shinjuku East Exit) because we use the booking and payment system under our Shinjuku East Exit clinic's contract - the booking and the payment are with us. If anything is unclear, contact us on our official LINE. If the booking site or the payment page will not open from overseas (403 error), connect to Japan via a VPN first and then open it.
1
Support

Book on our booking site

Choose a date and time on our booking site, then answer the questionnaire. Initial/follow-up fee ¥0. No payment fee. The booking site is in Japanese only; if anything is unclear, contact us on our official LINE.

2
Doctor

Online Consultation

Based on your questionnaire, we prescribe what suits your constitution and medical history. Returning patients with no change in their health and no questions can continue their prescription without a consultation (write “No consultation needed” in the questionnaire). Consultations are conducted through your questionnaire and chat on our official LINE; if you would prefer a video or phone consultation, let us know on LINE.

3
Payment support

Payment

After your consultation we email you a payment link (and also post the URL on LINE). On the payment page, enter your delivery address and card details and pay. Your card is charged for the medication only - there is no fee. Shipping is paid on delivery - please pay the driver when your parcel arrives.

4
Delivery

Medication Delivered

Delivered by Yamato Transport. Injectables go by cool delivery to your hotel or a Yamato Transport office.

Before you book (for visitors to Japan)
  • No health insurance card is needed. This is self-pay care, so no health insurance card, My Number insurance card or eligibility certificate is used, and no photo upload is required.
  • Bookings are made on our booking site, and all contact takes place on our official LINE. After booking, send “I have booked” and your name to our official LINE. We email you the payment link and also post it on LINE. The booking site is in Japanese only; if anything is unclear, contact us on our official LINE.
  • We ship all medication together on the day after your consultation, and we cannot accept requests for a specific shipping date. Please book about 5 days before the day you want to receive your medication. Those 5 days are calendar days, including weekends and public holidays. For example, if you want to receive your medication on the 26th of the month, have your consultation around the 21st. If you book later than that, your medication will not arrive in time, and if you book a week or more earlier, we will ask you to book again. Tell us the day you would like to receive your medication in the questionnaire that appears after you book.
DELIVERY

How to receive your medication

Mounjaro must be kept refrigerated. It ships by cold delivery, which puts a few conditions on how you can receive it.

Delivery to your home or where you are staying

We ship by refrigerated (cool) courier to your address in Japan. If you are out, the courier will redeliver.

Pickup at a Yamato Transport office

You can have your package held at a Yamato Transport office. When you pay, enter that office's address directly in the delivery address field on the payment page.

How to write the address

Write it as postal code → street address → Yamato Transport [office name], all in the same field. Without the office name we cannot tell which of the roughly 4,000 offices you mean, and we cannot ship. You can look the address up with the button below.

Writing only "hold at a Yamato office" is not enough — we cannot ship

Delivery to your hotel

We can deliver to the hotel where you are staying. Shipping is paid on delivery. If you receive it yourself you can pay by cash, contactless card or PayPay.

Hotel deliveries are also paid on delivery. If you receive it yourself you can pay by cash, contactless card or PayPay. If the front desk accepts it for you, please leave cash for the shipping fee with them.
Your consultation date and delivery date cannot be far apart
We ship all medication together on the day after your consultation, and we cannot accept requests for a specific shipping date. Please book about 5 days before the day you want to receive your medication. Those 5 days are calendar days, including weekends and public holidays. For example, if you want to receive your medication on the 26th of the month, have your consultation around the 21st. If you book later than that, your medication will not arrive in time, and if you book a week or more earlier, we will ask you to book again. Tell us the day you would like to receive your medication in the questionnaire that appears after you book.
You cannot collect your medication inside any airport terminal, including Kansai International Airport (関西国際空港) (you can collect it at a branch outside the airport)
Most Yamato Transport counters inside airport terminals only accept parcels that are being sent out, so they cannot hand a delivered parcel to you on the spot. This is the case at Kansai International (関西国際空港), Narita (成田), Haneda (羽田), Chubu (中部), Itami (伊丹), New Chitose (新千歳), Sendai (仙台), Fukuoka (福岡), Kitakyushu (北九州), Nagasaki (長崎), Kagoshima (鹿児島), Hiroshima (広島), Komatsu (小松), Shizuoka (静岡), Hakodate (函館) and Niigata (新潟) airports. There is no airport terminal where you can collect your medication. If you are flying through Kansai International Airport, please specify 泉佐野りんくう営業所 (Izumisano Rinku branch, near the airport; open every day of the year, 8:00-21:00). Please give the name exactly as written here in Japanese, as that is how it appears on the branch sign and on the delivery slip. Naha Airport (那覇空港) and Aso Kumamoto Airport (阿蘇くまもと空港) are different: at these two airports you cannot collect your medication inside the terminal, but you can collect it at a branch just outside the airport. For Naha Airport the branch is 那覇空港前営業所 (open every day of the year, 8:00-20:00), and for Aso Kumamoto Airport it is 阿蘇くまもと空港センター (open every day of the year, 8:00-18:00). In Kumamoto there is another branch with a very similar name, 阿蘇くまもと空港館内物流センター, and you cannot collect your medication there. The name that contains 館内物流 belongs to a different facility, so please be sure to specify 阿蘇くまもと空港センター. If you are flying through any other airport, you can still collect your medication at an ordinary branch outside the airport - a regular neighbourhood branch, rather than a counter carrying an airport name. Please open that branch's page on the Yamato Transport official website and check that its list of services says 荷物を受け取れる (parcels can be collected there). One thing to watch for: in and around railway stations there are shops that only hold luggage for travellers, and even when the sign shows a Yamato Transport branch, they do not hand over parcels.

🔴 Some branches inside or in front of stations are baggage-storage counters for travellers and do not hand parcels over. They show up prominently on maps but cannot be used for collection. Patients have specified "Yamato Namba Ekimae" and "Yamato Hakata Eki Chuogai", and we were unable to ship.

Branches you can collect from (verified by our clinic, August 2026)
Osaka
  • ヤマト運輸 大阪駅前第4ビル営業所(161340)
    〒530-0001 大阪府大阪市北区梅田1-11-4 大阪駅前第4ビル1F
    Open daily 8:00-21:00, no closing days
  • ヤマト運輸 黒門市場営業所(060304)
    〒542-0073 大阪府大阪市中央区日本橋1-14-10
    Weekdays 9:00-19:00 / weekends & holidays 9:00-17:00, no closing days
  • ヤマト運輸 新大阪駅東口営業所(068216)
    〒533-0033 大阪府大阪市東淀川区東中島1-21-15
    Open daily 8:00-21:00, no closing days (right by Shin-Osaka Station east exit)
  • ヤマト運輸 泉佐野りんくう営業所(069681)
    〒598-0048 大阪府泉佐野市りんくう往来北2-10
    Open daily 8:00-21:00, no closing days (near Kansai International Airport)
  • ヤマト運輸 元町1丁目営業所(060156)
    〒556-0016 大阪府大阪市浪速区元町1-9-10
    Weekdays 8:00-21:00, closed weekends & holidays (next to Namba Station / OCAT)
Fukuoka

Every branch in Fukuoka that accepts collection is closed on weekends and public holidays. Parcels are held for only three days, so please choose a delivery date that lets you collect on a weekday.

  • ヤマト運輸 博多駅前1丁目営業所(090450)
    〒812-0011 福岡県福岡市博多区博多駅前1-19-3 博多小松ビル1F
    Weekdays 8:00-19:00, closed weekends & holidays
  • ヤマト運輸 博多駅前3丁目営業所(090810)
    〒812-0011 福岡県福岡市博多区博多駅前3-6-1
    Weekdays 8:00-19:00, closed weekends & holidays
  • ヤマト運輸 博多駅東3丁目営業所(090301)
    〒812-0013 福岡県福岡市博多区博多駅東2-9-13
    Weekdays 8:00-19:00, closed weekends & holidays (Chikushi-guchi side)
  • ヤマト運輸 福岡舞鶴営業所(090490)
    〒810-0073 福岡県福岡市中央区舞鶴1-2-8 セントラルビル1F
    Weekdays 8:00-19:00, closed weekends & holidays

Our clinic checked the above on Yamato Transport's official pages - whether each branch hands over parcels, and its opening hours (as of August 2026). Opening hours can change, so please check again before you set out. If you would like a branch that is not on our list, open that branch's page on the Yamato Transport official website and check that its list of services says 荷物を受け取れる (parcels can be collected there). Please also note that in and around railway stations there are shops that only hold luggage for travellers, and even when the sign shows a Yamato Transport branch, they do not hand over parcels.

Please read before you book
We cannot change the delivery address after payment

Cancelling a booking is free at any time before the consultation. However, once payment is complete, our system does not allow us to change the delivery address. If a change becomes necessary, you will need to contact Yamato Transport yourself using the tracking number we send you, and a second shipping charge will apply.

If the parcel is returned undelivered, the medication cost cannot be refunded

If we cannot deliver because of an incorrect address, a name that does not exist, or a phone number that cannot be reached - details registered by the patient - the medication is returned to us. Refrigerated medication cannot have its temperature chain guaranteed, so it is disposed of. As a rule we cannot re-send it, and the medication cost cannot be refunded. See "Cancellation and refunds" for details.

We do not ship the medication in its outer box

We take the medication out of its outer cartons and send everything together in a single cool box. Many patients are prescribed several months at once, and keeping the outer cartons would mean more parcels and higher shipping costs. We are also unable to accommodate requests for a particular box size. We send a prescription certificate free of charge to everyone who receives a prescription, without your having to ask for it. It is a document written in both English and Japanese, and you can present it at customs. We send it as a PDF to your registered email address and to our official LINE account.

Apple's "Hide My Email" addresses cannot be used

If you register an address ending in @privaterelay.appleid.com (Apple's "Hide My Email"), our emails will not reach you. We cannot send your tracking number, which leaves us no way to tell you where your parcel is. Please register the email address you use every day. If you have already registered one, add our official LINE account - we will send the tracking number there as well.

Adding our official LINE account is required

After you book, we contact you through our official LINE account, so please be sure to add us as a friend. We send any urgent messages through our official LINE account, and if you have not added us, we have no way of reaching you. When you add us, please set your own LINE profile name to your real name, the same name you register on our booking site. If your profile name is a nickname, or a name made up only of emoji or symbols, we cannot tell which booking is yours and we are unable to contact you. Please understand in advance that we cannot accept responsibility for any disadvantage that arises if we are unable to confirm your name and therefore cannot reach you. Apart from messages about your booking and your medication, we will not send you anything: no advertising and no mass mailings.

Branches hold parcels for three days. After that the parcel is returned to us, so please collect it soon after it arrives. About a third of all branches close on weekends and public holidays, so a weekend in between can make collection impossible. Please choose from the list above, or ask for hotel delivery if you need to collect at a weekend.
You need ID to collect a parcel; please bring your passport. Showing the payment confirmation email as well makes it more straightforward.
Shipping is from ¥1,215 (Kanto reference) and varies by region. All shipping is paid on delivery - pay the driver when your parcel arrives.
Pickup at the clinic is not available. Our online service delivers medication by courier only.
Source for the storage conditions: Mounjaro package insert (Eli Lilly Japan) medical.lilly.com

CANCELLATION POLICY

Cancellation and refunds

We do not charge any cancellation or termination fees. We do not deliver on a recurring schedule, and there is no automatic renewal. Payment is taken at the time of your consultation, and cancelling before your consultation is always free.

Before the consultation
FreeJust tell us "cancel" on our official LINE. There is no charge if you cancel before paying. We will deactivate the payment link.
After the consultation, before payment
FreeNo payment has been taken yet.
After payment, before dispatch
Refunds are not available as a ruleEach prescription is prepared individually for you and kept refrigerated. Once prepared, it cannot be passed on to another patient, so we do not offer refunds after payment as a rule. If you have unavoidable circumstances, please contact us through our official LINE account as soon as possible and we will discuss your case individually. Where a refund is made, shipping and bank transfer fees are deducted. Preparation for shipping begins on the next business day after payment.
After dispatch
Cancellation and refunds are not availableUnder Japanese pharmaceutical law, prescribed medication that has been dispatched cannot be returned or refunded.
If the parcel cannot be delivered and is returned

If we cannot deliver because of incomplete details registered by the patient - an incorrect address, a name that does not exist, a phone number that cannot be reached, or a parcel not collected within the holding period - the medication comes back to us. Refrigerated medication cannot have its temperature chain guaranteed once it has travelled back, so it is disposed of. As a rule we cannot re-send it, and the medication cost cannot be refunded. Before you book, please make sure the address you give is one where you can definitely receive the parcel on the day it arrives.

Changing the delivery address after payment

We cannot change the delivery address after payment. If a change becomes necessary, you will need to contact Yamato Transport yourself using the tracking number we send you, and a second shipping charge will apply.

CLINICAL DATA

How much can I lose with Mounjaro?

Reference figures based on SURMOUNT-1, an international clinical trial with 2,539 participants. Average weight loss at 72 weeks differed by dose: 5mg -15.0%, 10mg -19.5%, 15mg -20.9%.

About -6%
〜2 Months:Appetite settles, weight begins to change
  • 50kg → about -3kg (ref.)
  • 65kg → about -3.9kg (ref.)
  • 80kg → about -4.8kg (ref.)
About -10%
〜6 Months:Fullness becomes easier to maintain; easier to continue treatment
  • 50kg → about -5kg (ref.)
  • 65kg → about -6.5kg (ref.)
  • 80kg → about -8kg (ref.)
About -19 to -21%
〜12+ Months:72 weeks (~17 months): 20.9% average reduction on 15mg (clinical ref.)
  • 50kg → about -9.5〜10.5kg (ref.)
  • 65kg → about -12〜14kg (ref.)
  • 80kg → about -15〜17kg (ref.)

※Source: Jastreboff AM et al., "Tirzepatide Once Weekly for the Treatment of Obesity," New England Journal of Medicine (2022). A reference simulation based on the dose-by-dose results of a 72-week trial of tirzepatide with 2,539 participants. Outcomes are not guaranteed and vary widely with metabolism, age, diet and exercise habits. ※ Mounjaro is not approved in Japan as an obesity treatment. As private practice (not covered by insurance), it is outside the drug side effect relief program.

Nurse character
SAFETY INFO

Side Effects & Precautions

Our nurse character explains this accurately, in line with medical advertising guidelines.

Mounjaro

Main Side Effects Nausea, vomiting, diarrhea, constipation, decreased appetite. Common at start or after dose increase; usually subsides within weeks.

Caution Acute pancreatitis, gallstones, hypoglycemia (with other meds), anaphylaxis

Who Cannot Use Type 1 diabetes, diabetic ketoacidosis, diabetic coma or precoma; emergencies such as severe infection or surgery; a history of hypersensitivity to the ingredients; pregnancy or possible pregnancy

Dapagliflozin

Main Side Effects Frequent urination, UTI, genital infection, hypoglycemia (with other meds)

Caution Dehydration, ketoacidosis (rare), skin reactions

Who Cannot Use Severe ketosis, diabetic coma or precoma; severe infection, the period around surgery, or serious trauma; a history of hypersensitivity to the ingredients; severe renal impairment (no benefit expected); pregnancy or possible pregnancy

Metformin

Main Side Effects GI symptoms (nausea, diarrhea, abdominal pain). Taking after meals can reduce symptoms.

Caution Lactic acidosis (rare, serious). Special caution for those with kidney problems.

Who Cannot Use A history of lactic acidosis; severe renal impairment (eGFR below 30) or dialysis; severe hepatic impairment; severe ketosis, diabetic coma or precoma; severe infection, the period around surgery, or serious trauma; excessive alcohol intake; pregnancy

Breastfeeding is not listed as a contraindication for any of these medicines, but each is handled differently. For Mounjaro, continuing or stopping breastfeeding is decided by weighing the benefit of treatment against the benefit of breastfeeding; with Dapagliflozin, breastfeeding should be avoided while taking it. If you are breastfeeding, including on metformin, please tell us at your consultation.

Weight loss prescriptions at our clinic are off-label (private practice). Insurance not applicable. Results vary and specific outcomes are not guaranteed.If side effects occur, please consult via LINE (10:00–19:00).

HOW TO USE

How to Use Mounjaro・Injection Guide

Reassuring even for first-timers - our nurse character walks you through each step.

Nurse character

Injection Basics

Once a week, on the same day each week. Any time of day, before or after meals. If you change the day, leave at least 72 hours (3 days) since the last dose.

Missed a dose? If the next scheduled day is 3 or more days away, inject when you remember; if less than 3 days, skip it and resume on the next scheduled day.

Remove cap

Pull cap straight off the pen

Place on skin

Press the clear base firmly against the injection site (abdomen / front of thigh / outer upper arm). Shift the spot 2-3 cm each time. The abdomen and thigh are easiest to reach yourself; the upper arm is better suited to having someone else inject.

Unlock

Turn the dial to 'unlock' until it stops

Press button

Press the purple button slowly and listen for two clicks (1st = start, 2nd = finished, within 10 seconds).

Storage: keep unopened pens refrigerated (2-8C) and never freeze them. Do not put used needles straight into household rubbish - follow the guidance of your local authority. See Eli Lilly Japan's official page for the actual injection procedure.
Support character
FAQ

Frequently Asked Questions

Answered by our support character.

Q.Are initial/follow-up fees charged?+
Both initial and follow-up consultation fees are ¥0. There are only two costs: the medication and cool-delivery shipping at cost, and there is no payment fee. The totals in the price table include both. All listed prices include consumption tax.
Q.What dose does Mounjaro start at?+
We normally start at the lowest dose, 2.5 mg, so your body can adjust safely through the early period when side effects (nausea, loose stools) are most likely. Many people get sufficient results at 5 mg; the doctor decides on increasing to 7.5 mg based on your build and preference. We never push a dose increase. Results vary by individual. Private practice (not covered by insurance).
Q.Are there cancellation fees?+
Cancellation and termination fees are both ¥0. There is no ongoing commitment, and you may stop at any time. We do not deliver on a recurring schedule. A prescription for just one month (4 pens) is perfectly fine. There is no auto-renewal, and booking again is entirely up to you.
Q.Is this a recurring delivery? Can I be prescribed just one month?+
Cancellation and termination fees are both ¥0. There is no ongoing commitment, and you may stop at any time. We do not deliver on a recurring schedule. A prescription for just one month (4 pens) is perfectly fine. There is no auto-renewal, and booking again is entirely up to you. If you would like to continue, simply book another consultation when you are ready.
Q.How much is shipping?+
Everything ships by cool delivery, 60-size (from ¥1,215, Kanto). Oral medication such as Dapagliflozin goes in the same box as the injectables, so you pay shipping only once. Shipping is paid on delivery — to the driver, at a Yamato office, or at your hotel.
Q.Is insurance applicable?+
No, all weight loss prescriptions at our clinic are private practice (not covered by insurance).
Q.Do I need a Japanese health insurance card or My Number card?+
No. All of our weight-loss prescriptions are self-pay care (not covered by insurance), so no health insurance card, My Number insurance card or eligibility certificate is required, and you do not need to upload a photo of one.
Q.What if the medication doesn't work for me?+
There is no lock-in, so you can stop at any time (cancellation and termination fees are ¥0). Dose changes or switching to another medication are handled after a consultation. Please note that under Japan's Pharmaceuticals and Medical Devices Act, medication already prescribed and shipped cannot generally be returned or refunded.
Q.Do I have to go to Shinjuku if I have side effects?+
First of all, there is no need to worry excessively. Mild symptoms such as nausea, loose stools or fatigue can appear temporarily at the start, but they usually settle within a few days to a few weeks. If anything concerns you, consult the doctor via our official LINE (10:00-19:00); we will advise on dose adjustment or how to manage it. Please contact us without hesitation if you feel unwell.
Q.Can I receive it discreetly without my family knowing?+
Yes. You can have your parcel held for you at your nearest Yamato Transport (ヤマト運輸) branch. This service is called eigyosho-dome (営業所止め). When you pay, please enter the branch's name and address directly into the delivery address field on the payment page. You enter the delivery address yourself on the payment page when you pay. Between your payment and dispatch, the delivery address cannot be changed. Because of the way the payment system works, we have no way to change it either. After dispatch, please use the tracking number we send you and contact Yamato Transport yourself to request a change of delivery date and delivery location. Yamato Transport's Customer Service Center can be reached on 0570-200-000. If you register with Kuroneko Members (クロネコメンバーズ), which is free, you can also make the change online. Please bring photo identification such as your passport when you collect your parcel.
Q.What payment methods can I use?+
We accept credit cards only. You pay by VISA or Mastercard credit card on the payment page of the payment link we send you (JCB, American Express, Diners and debit cards cannot be used). Bank transfer, cash, convenience-store payment, e-money and deferred payment are not available. Note that your card covers the medication only; there is no fee. Shipping (from ¥1,215) is paid on delivery, so please pay on delivery - by cash, contactless card, transport IC card or QR payment such as PayPay .
Q.How do I pay the shipping fee?+
Shipping is paid on delivery. Your card is charged for the medication only; the shipping fee (from ¥1,215) is paid when you receive the parcel. This applies to home, Yamato office and hotel deliveries alike. You can pay by cash, contactless credit card, transport IC cards such as Suica, or QR payments such as PayPay, Rakuten Pay and d-barai. Cards are contactless only - chip-and-PIN or signature payments are not accepted.
Q.Is consumption tax added to the listed prices?+
Listed prices include Japanese consumption tax. Self-pay care is a taxable transaction, but the clinic absorbs the tax and it is already included in the listed price. The totals in the price table already cover the medication and cool-delivery shipping; nothing else is charged. Outside Kanto only the shipping difference changes.
Q.Can I use a credit card issued outside Japan?+
Only VISA and Mastercard credit cards can be used for payment. A card issued outside Japan is fine as long as it is a VISA or Mastercard credit card, and this includes cards issued in Korea. JCB, American Express and Diners cards, and debit, check and prepaid cards, cannot be used. Please also check your credit limit and expiry date. If the payment still does not go through, contact us on our official LINE and we will advise you individually. Paying the shipping fee on delivery is separate - cash, contactless card, transport IC cards and QR payments such as PayPay can all be used there.
Q.Where can I receive the medication? Can I pick it up at a store?+
You can choose your home address (where you are staying in Japan), your nearest Yamato Transport office, or the hotel where you are staying. Pickup at the clinic is not available. If it goes to a hotel, put it in the room fridge as soon as you receive it. A Yamato office holds the parcel for 3 days. You need photo ID such as a passport to collect it, and showing the payment confirmation email as well makes it more straightforward.
Q.I am not a Japanese national. Can I still receive treatment?+
Yes. You can use our online consultation regardless of nationality. You can also book and pay while you are still overseas and receive your medication after you arrive in Japan. You will need photo ID (passport, residence card, etc.), a delivery address or pickup office in Japan, and a smartphone with an internet connection. Note that the booking site and the payment page are in Japanese only; if anything is unclear, contact us on our official LINE. If they will not open from outside Japan (403 error), connect to Japan via a VPN first and then open it.
Q.I do not have a Japanese phone number. Can I still have a consultation?+
Yes. You do not need a Japanese phone number. What to enter as the delivery phone number on the payment page depends on where the parcel is going. For delivery to a home, a friend's home, or a hotel, enter a number that can actually be reached (the Japanese number of the person receiving the medication is fine). The delivery company bringing your medication will call it. You also enter a phone number when you register on our booking site. If you do not have a Japanese phone number, enter “08012345678” in the registration phone field (your hotel's phone number is also fine).
Q.Can I book a consultation long before the date I want the medication delivered?+
No, we cannot accept bookings made long in advance. We ship all medication together on the day after your consultation, and we cannot accept requests for a specific shipping date. Please book about 5 days before the day you want to receive your medication. Those 5 days are calendar days, including weekends and public holidays. For example, if you want to receive your medication on the 26th of the month, have your consultation around the 21st. If you book later than that, your medication will not arrive in time, and if you book a week or more earlier, we will ask you to book again. Tell us the day you would like to receive your medication in the questionnaire that appears after you book.
Q.Does the medication come in its box? Are alcohol swabs included?+
We take the pens out of their outer cartons and pack everything together into a single cool box. Many patients are prescribed several months at once, and keeping the outer cartons would mean more parcels and higher shipping costs. We are sorry, but we cannot deliver the medication in its outer carton. We send a prescription certificate free of charge to everyone who receives a prescription, without your having to ask for it. It is a document written in both English and Japanese, and you can present it at customs. Alcohol swabs (disinfectant wipes) are not included. They are sold at pharmacies and drugstores, so please pick some up yourself.
Q.Where can I find the tracking number after dispatch?+
After we ship your medication, we email the tracking number (the waybill number) to the email address you registered with us. You do not need to chase us for it. We also let you know on our official LINE. We ship on the next business day after your consultation and payment are complete. Delivery is usually the day after we ship within the Kanto region, and two days after we ship for other regions. Some areas, such as Hokkaido, Okinawa and remote islands, can take longer than that. Please note that the shipping date and the delivery date are not the same. If the email does not arrive, or if you have not heard from us after a while, please let us know on our official LINE account. We will check right away and reply to you.
Q.Can I get several different doses in one order?+
Yes. We can supply several doses together to match your titration plan (for example 2 months of 2.5mg + 2 months of 5mg + 2 months of 7.5mg). The price is the sum of each dose, with shipping charged once, all in a single box. Please allow at least four weeks between dose increases and go by how you feel - we do not recommend increasing while side effects are still present. Tell us your preferred combination on our official LINE.
Q.Is the parcel kept refrigerated while it waits at the Yamato centre?+
Yes. It travels by refrigerated courier, so it stays chilled while it waits at the service centre - no concern even in summer. It is held for 3 days including the day it arrives; after that it is returned, so please collect it promptly. Take it home in a cool bag and put it in the hotel room fridge or your own fridge (2-8°C). Keep a towel between the pack and the ice pack, as direct contact can freeze it. Once frozen, it can no longer be used.
Q.Can I get more than 4 months at once?+
Yes. There is no upper limit on how many months we can prescribe. The monthly medication cost does not change with the number of months, so 4 months of 2.5mg is ¥8,000 × 4 = ¥32,000. The price simulator above calculates up to 12 months. Even for a large order it is one consultation and one delivery, so shipping is charged once.
Q.Can I change the delivery location or date later on?+
It depends on when you ask. You enter the delivery address yourself on the payment page when you pay. Between your payment and dispatch, the delivery address cannot be changed. Because of the way the payment system works, we have no way to change it either. After dispatch, please use the tracking number we send you and contact Yamato Transport (ヤマト運輸) yourself to request a change of delivery date and delivery location. Yamato Transport's Customer Service Center can be reached on 0570-200-000. If you register with Kuroneko Members (クロネコメンバーズ), which is free, you can also make the change online. Please note that we are unable to make these arrangements on your behalf at any stage. A great many patients use our clinic every day, and if we handled delivery changes one by one, mistakes in delivery could occur. We are sorry to ask this of you, and we are grateful for your understanding. The surest approach is to choose, at the time of booking, a place where you know you will be able to receive the parcel.
Q.Does the price change with the dose?+
Yes. The drug cost differs for 2.5mg, 5mg and 7.5mg. One-month totals are 2.5mg ¥9,215 / 5mg ¥16,215 / 7.5mg ¥23,215 (drug + cool-delivery shipping ¥1,215). See the dose tabs in the price table for details.
Q.Can dapagliflozin be used together with Mounjaro?+
Yes. Mounjaro curbs appetite so you eat less, while dapagliflozin pushes the sugar you do take in out through urine. Because they work differently, they are sometimes used together. Ordered alongside Mounjaro, the only extra cost is the medication itself (from ¥3,980 per month). Note that water leaves with the sugar, so dehydration becomes easier — drink regularly through the day. It is not suitable if your kidney function is reduced or you get repeated urinary tract infections. Please discuss it at your consultation.
Q.Is the price different in-person vs. online?+
The price is the same in person and online; nothing costs more because you consult online. First and follow-up consultations are ¥0. There are only two costs: the medication and cool-delivery shipping. The totals in the price table include both.
Q.Can I switch from another clinic?+
Yes. Tell us your current medication, dose and how long you have been taking it in the questionnaire. The doctor will assess whether continuing is appropriate and take over the prescription as needed. There is no transfer discount or special rate, but the first consultation is ¥0.
Q.My weight loss has stalled (plateau). What should I do?+
The strong “stomach-slowing effect” seen early in treatment often eases as you continue (tolerance). Prolonged drug action can also reduce receptor sensitivity — known as downregulation, which is different from dependency. Reviewing the dose, a temporary reduction or pause, or combining a drug that works by a different mechanism (Dapagliflozin, metformin, etc.) can help you get past a plateau. Management varies by individual: do not raise or stop your dose on your own, and always consult your doctor. Results vary from person to person.
AFTER YOU START

Questions after you start

The questions we are actually asked most: nausea, missed doses, storage, and how to stop.

Q.What should I do if I feel nauseous?+
Nausea is most likely right after you start and right after a dose increase. The Japanese package insert for Mounjaro reports nausea, vomiting, diarrhoea, constipation and abdominal pain at a frequency of 5% or more. It happens because the stomach empties more slowly, and it usually settles as you continue. Eat smaller portions, avoid fatty food, and sip fluids often. If it is still hard to cope with, do not put up with it - contact us on our official LINE. We can hold off on increasing the dose, or go back to the previous one. If you keep vomiting and cannot keep fluids down, contact us without waiting for your next consultation.

Source kegg.jp u-fukui.ac.jp

Q.I missed a dose. When should I take it?+
The package insert sets out a 72-hour rule. If your next scheduled dose is 3 days (72 hours) or more away, inject as soon as you notice, then go back to your usual day. If it is less than 3 days (72 hours) away, skip that dose and take the next one on schedule. Never take two doses together - side effects can be severe. You choose your own injection day, so a phone reminder helps if you tend to forget. Ask us if you are unsure.

Source kegg.jp pmda.go.jp

Q.How should I store the medicine?+
The fridge is the default. The package insert says to avoid freezing and store at 2-8C, protected from light. Keep it inside the fridge rather than in the door, but away from the cold-air vent. Once a pen has frozen it cannot be used, even if it looks normal - discard it. When a fridge is not available, you may keep it in its outer carton somewhere below 30C and use it within 21 days. You cannot put it back in the fridge and restart the count. Avoid direct sunlight and the inside of a car in summer.

Source kegg.jp

Q.Can I take it home on the plane?+
Keep it cold. Use a cool bag with an ice pack, but put a towel between the pack and the pen - direct contact can freeze it. If your hotel has no fridge, check that you can stay within the room-temperature allowance: below 30C and used within 21 days. You may carry needles and injectable medicine on board if you declare them at security. We can issue a prescription certificate, so ask us on LINE. Import rules differ by country and we have not verified them all [unverified], so please check the rules of the country you are returning to.

Source ana.co.jp jal.co.jp

Q.Where and how do I inject?+
It is a subcutaneous injection. The product's package leaflet approves three sites: the abdomen, the thigh, and the upper arm. If you are injecting yourself, the abdomen and the thigh are the easiest to reach; the upper arm is better suited to cases where a family member gives you the injection. Even within the same site, the leaflet specifies moving the spot by 2-3 cm each time. Please avoid the area around your navel, and do not inject the same spot twice in a row. There are four steps. 1. Remove the cap. 2. Press the clear base firmly against your skin. 3. Release the lock. 4. Press the button slowly and listen for two clicks. The first click means the injection has started, and the second means it is finished. The second click takes about 10 seconds to come, so keep the button held down and keep the base pressed against your skin until you hear it. The needle is fine and single-use. For your first injection we will talk you through the steps during your consultation, so please ask us there about anything you are unsure of. You can also watch a video and read a booklet on how to inject on the official website of the manufacturer, Eli Lilly Japan. The page is in Japanese, but the video alone is enough to follow the steps. Please use the button below to go there.

Source kegg.jp

Q.Can I drink alcohol?+
There is no blanket ban, but keep the amount and frequency low. Three reasons. First, alcohol is a leading cause of acute pancreatitis; a nationwide survey in Japan reported that roughly half of acute pancreatitis in men was alcohol-related, and acute pancreatitis is listed as a serious adverse reaction for Mounjaro. Second, alcohol tends to release the brake on appetite, which leads to overeating afterwards. Third, if you also take metformin, note that the Japan Diabetes Society lists excessive alcohol intake as a risk factor for lactic acidosis. A specific drinking limit for GLP-1 drugs themselves is [unverified]. Raise it at your consultation if you are concerned.

Source nittokyo.or.jp jstage.jst.go.jp

Q.My weight has stopped moving. What should I do?+
First, this is a normal response. As weight comes down, the body adjusts by lowering how much energy it burns (metabolic adaptation). A study that followed people for six years after major weight loss found resting metabolism lower than body size alone would predict, and that it stayed that way. Cutting food drastically at this point costs you muscle and makes regain more likely. Do three things: keep protein up, get your activity back to where it was, and look at numbers other than weight. If nothing moves for several weeks, raise it at your consultation - the dose can be reviewed. A plateau is not failure; it is your body settling into a new weight.

Source pubmed.ncbi.nlm.nih.gov

Q.Besides weight, what should I be watching?+
Four things: waist circumference, body-fat percentage, blood pressure and blood tests. The Japan Society for the Study of Obesity's 2022 guideline states that the aim of treatment is not the number on the scale but preventing and improving the health problems that come with obesity. The target it gives is a reduction of 3% or more of current body weight over three to six months - about 2 kg for someone weighing 70 kg. That sounds small, but the guideline's position is that even this much can improve blood glucose, blood pressure and lipids. Plenty of people see their waist shrink and their blood tests improve while the scale stays flat. Do not judge by one number.

Source jasso.or.jp

Q.Will I regain the weight if I stop?+
Trial data says regain is likely if you do nothing. In the SURMOUNT-4 trial of tirzepatide, participants lost an average of 20.9% over 36 weeks; those who stayed on the drug lost a further 5.5%, while those switched to placebo gained an average of 14.0% over the next 52 weeks. Even so, at the one-year mark they were still around 10% lighter than at the start. What matters is designing how you stop. Rather than going to zero overnight, step the dose down while first locking in habits around food, activity and regular weighing. We plan the exit with you.

Source pubmed.ncbi.nlm.nih.gov

Q.How long do I need to keep going?+
There is no fixed end date. The 2022 obesity guideline treats obesity as a long-term condition, much like hypertension, and sets out that once the first target (3% or more of current body weight) is reached, the target should be reset in light of how the associated health problems are doing. In other words, the goal is allowed to move. For patients approaching their target we switch from losing to holding, and consider lowering the dose, spacing injections out, or taking a break. Talk to us before stopping abruptly on your own.

Source jasso.or.jp

Q.My digestion has changed+
Both constipation and diarrhoea can happen. The package insert reports nausea, vomiting, diarrhoea, constipation and abdominal pain at 5% or more. Gut motility changes, and it usually settles as you continue. For constipation, pay attention to fluids and fibre - when you eat less, fibre tends to drop with it. Gentle movement helps too. For diarrhoea, cut back on fatty and cold food and alcohol, and replace fluids and salt. If either does not improve within a few days, or comes with severe abdominal pain or blood in the stool, do not wait it out with over-the-counter medicine - contact us.

Source kegg.jp u-fukui.ac.jp

Q.When can I go up to 5mg?+
The package insert specifies starting at 2.5 mg once weekly and moving to 5 mg once weekly after four weeks. Any further increase is also in 2.5 mg steps, at intervals of at least four weeks. Stepping up gradually eases digestive symptoms such as nausea and lets the body adjust. We understand wanting results sooner, but we decide on an increase after seeing how you are doing. In practice many people find 5 mg does enough. We will not increase the dose while side effects persist or while you are not eating properly. Tell us at your consultation if you would like to go up.

Source kegg.jp pmda.go.jp

Q.Can I inject when I have a cold or stomach bug?+
A sick day means fever, vomiting or diarrhoea that stops you eating and drinking properly. It is safer to hold the injection while that lasts. Mounjaro slows gastric emptying, so injecting on top of existing nausea or diarrhoea can compound the symptoms and worsen dehydration. Prioritise fluids - an oral rehydration solution if you have one. Skipping one dose is fine; go back to your usual day once you have recovered. Contact us if you are unsure, or if you cannot keep fluids down for a whole day. In Japan you can attend an emergency outpatient department at night and on holidays.

Source dmic.jihs.go.jp kegg.jp

Q.Which symptoms mean I should see a doctor straight away?+
The main sign is severe, persistent pain from the upper abdomen through to the back. Japan's Ministry of Health, Labour and Welfare, in Pharmaceuticals and Medical Devices Safety Information No. 406, alerts prescribers to watch for signs and symptoms of acute pancreatitis with GLP-1 and GIP/GLP-1 receptor agonists. The package insert lists acute pancreatitis (under 0.1%), cholecystitis and cholangitis, ileus and anaphylaxis as serious adverse reactions. Severe abdominal pain, repeated vomiting, fever, yellowing of the skin or the whites of the eyes, or severe fatigue: if any of these appear, stop using the medicine and see a doctor without waiting for your next consultation. In Japan you can attend an emergency outpatient department at night and on holidays.

Source mhlw.go.jp kegg.jp

Q.Can it cause hypoglycaemia?+
Used on its own, Mounjaro is unlikely to cause hypoglycaemia, because GLP-1 and GIP act more strongly when blood glucose is high. That said, the package insert lists hypoglycaemia as a serious adverse reaction, and care is needed when it is combined with other glucose-lowering drugs such as insulin or sulfonylureas. Always declare your medical history and current medicines at your consultation. If you get cold sweats, palpitations, shaking hands, intense hunger or feel mentally foggy, take glucose or a sugary drink. Tell us if it keeps happening.

Source dmic.jihs.go.jp kegg.jp

Q.Will I lose muscle too?+
Not all of the weight you lose is fat. In the body-composition substudy of SURMOUNT-1, over 72 weeks body weight fell 21.3%, fat mass 33.9% and lean mass 10.9% - roughly 75% of the weight lost was fat and 25% was lean tissue. The ratio was much the same in the placebo group, so this is not specific to the drug. Even so, muscle is worth protecting. Get enough protein and keep doing resistance exercise. When appetite drops, protein is usually the first thing to fall, so make a point of eggs, fish, meat and soy foods.

Source pubmed.ncbi.nlm.nih.gov

Q.How much water should I drink?+
Increase it deliberately. When you eat less, the water that used to come from food drops too - more so if you have nausea or diarrhoea. This matters especially if you also take an SGLT2 inhibitor such as Dapagliflozin, because water leaves with the glucose in your urine. The right amount depends on your build, your conditions and the season, so there is no single figure, but the principle is little and often, before you feel thirsty. Avoid drinking a very large volume all at once; rarely this can cause hyponatraemia. If you have a heart or kidney condition, discuss the amount at your consultation.

Source dm-rg.net mhlw.go.jp

Q.Can I use it while pregnant or breastfeeding?+
No. The package insert states that it must not be given to women who are pregnant or may be pregnant. For women who are breastfeeding, the decision to continue or stop is to be made weighing the benefit of treatment against the benefit of breastfeeding. If you are planning a pregnancy, discuss the timing of stopping in advance. If you find you are pregnant while using it, do not agonise over it alone - contact your obstetrician and us first. We always check this in the first-visit questionnaire, so please answer accurately if it applies to you.

Source kegg.jp

Q.How do I dispose of used pens and needles?+
Do not put them straight into household rubbish. Used needles can cause needlestick injuries during waste collection, so Japan's Ministry of the Environment guidance says that in principle the prescribing medical institution should take them back. The Japan Association for Diabetes Education and Care also warns against putting them in bottles, cans or PET bottles. If you dispose of them in Japan, follow the guidance of the local authority where you are staying. If you plan to dispose of them after you get home, carry them in a puncture-proof container and follow the rules of your own country. Passing on or selling leftover medicine to another person is an offence under Japan's Pharmaceuticals and Medical Devices Act. Never do it. If your local authority will not take them, post them to UBCLINIC Shinjuku Higashiguchi (Shinjuku ex II 6F, 1-16-1 Kabukicho, Shinjuku-ku, Tokyo) by Letter Pack or ordinary mail (non-standard size). We cannot accept cash-on-delivery.

Source env.go.jp nittokyo.or.jp

Q.Some mornings the scale is higher+
Body weight swings by 1-2 kg within a single day. Most of that is water, what you have eaten and what is still in your bowel - not new fat. After a salty meal your body holds water and the scale goes up, but it comes back within a day or two. Women can also see swings of 1-3 kg across the menstrual cycle. If you weigh yourself, keep the conditions the same: first thing in the morning, after using the toilet, in the same clothes, on the same scale. It will still go up and down; that is normal. What matters is not the day-to-day change but whether the one-to-two-week average is trending down. People who do not ride the daily numbers tend to keep going longer.

Source tanita.co.jp otsuka.co.jp

REVIEWS

What our patients say

You can read the Google reviews written by people who actually came to us. We cannot edit any of them, good or bad.

Read the reviews on Google

This opens the Google Business Profile of UB Clinic Shinjuku Higashiguchi. The online service is run by the same clinic.

If your medication has arrived
  • Your review appears under your Google account display name. You can change that name before posting if you would rather not show your real one.
  • Write what went well and what did not. Nothing about how we treat you changes with what you write.
  • Writing a review is entirely optional. Your consultation, prescription, fees and delivery are the same either way.
  • We do not give any reward or discount for reviews. Google's policies prohibit it.
Illustration of the doctor
DOCTOR
Dr. Naoki Sekiguchi
  • 2011 - Licensed as a physician in Japan
  • 2018 - Trained in general medicine at a university hospital in Tokyo
  • Then - Worked in the emergency department of a general hospital in Tokyo
  • Now - Sees patients 3 days a week in internal medicine clinics and on home visits
  • Also covers emergency shifts on weekends and over the New Year period
Certified Internist, Japanese Society of Internal Medicine

I still see patients three days a week, in clinic and on home visits.

Working in emergency medicine, I have met the same thought many times: if only the weight had come down sooner. Type 2 diabetes, high blood pressure, sleep apnoea - all of them ease as weight falls.

Weight loss is often treated as a question of appearance. To me it is treatment, aimed at the illnesses that would otherwise come later.

I see online consultation as a way in for people who are too busy to attend a clinic. We take the time to listen properly to each patient.

Safely, and within what you can sustain. Let me help you with that.

Dr. Naoki Sekiguchi, UB Clinic Online

Selected publications

  1. 関口直樹, 赤穂理絵. HIV関連神経認知機能障害HIV-associated neurocognitive disorder. 精神科治療学 34(増刊):56-58, 星和書店, 2019.
  2. 関口直樹, 稲田健. うつ病におけるベンゾジアゼピン系薬剤併用の利益と問題点Benzodiazepines in the treatment of depression: benefits and problems. 臨床精神薬理 18(10):1285-1291, 星和書店, 2015.
  3. 関口直樹, 稲田健, 石郷岡純. 睡眠薬の適切な中止方法How to discontinue hypnotics appropriately. ねむりとマネージメント 1(1):28-32, 先端医学社, 2014.
  4. 関口直樹, ほか. 高齢者における推定糸球体濾過量の算出についてEstimating GFR in the elderly. 東京女子医科大学雑誌 83(1):47-48, 2013.
FOR VISITORS TO JAPAN

For visitors staying in Japan

How to book from overseas and receive your medication after you arrive in Japan, plus the points people most often get stuck on.

BOOKING AND MEDICAL QUESTIONS — POSSIBLE FROM OVERSEAS
1

Add our official LINE account

We handle everything through our official LINE account, so please add us first. Once your consultation is done and you no longer need it, you are welcome to block us at any time. We also send out offers and useful updates from time to time.

💬Add us on LINE

2

Book on our booking site

☝️Choose a date and book

Bookings are taken on our booking site, and enquiries on our official LINE. The booking site is in Japanese only; if anything is unclear, contact us on our official LINE. You pay through a payment link that we send you by email. The booking site and the payment page may not open from outside Japan (403 error); if so, connect to Japan via a VPN first and then open it.

Please finish your booking and your consultation about 5 days before the day you want to receive your medication in Japan. Count back from the day you receive your medication, not from the day you travel to Japan. Those 5 days are calendar days, including weekends and public holidays. For example, if you want to receive your medication on the 26th of the month, have your consultation around the 21st. If you book a week or more earlier, we will ask you to book again. You are welcome to book, have your consultation and pay while you are still overseas. You then receive your medication after you arrive in Japan, at your hotel or at a Yamato Transport office.

Three points people get stuck on when booking and paying
  • Phone number field: what to enter depends on where the parcel is going. For delivery to a home, a friend's home, or a hotel, enter a number that can actually be reached; if you do not have a Japanese number, you may use the Japanese number of the person receiving the medication. The delivery company will call this number, and an unreachable number can lead to failed delivery and return of the parcel. You also enter a phone number when you register on our booking site. If you do not have a Japanese phone number, enter “08012345678” in the registration phone field (your hotel's phone number is also fine). The consultation is conducted in English or through a translation app.
  • Booking site and payment page: The booking site and the payment page are in Japanese only. The clinic name shows as "UBCLINIC 新宿東口" (Shinjuku East Exit) because we use the booking and payment system under our Shinjuku East Exit clinic's contract - the booking and the payment are with us. If anything is unclear, contact us on our official LINE. If the booking site or the payment page will not open from overseas (403 error), connect to Japan via a VPN first and then open it.
  • Email address: the booking site's confirmation email and our payment link are sent to the email address you register. If they do not arrive, check your spam folder. Apple's "Hide My Email" addresses (@privaterelay.appleid.com) cannot be used.
3

Answer the questionnaire

Write in the medicine, dose and number of months you would like. Please also note any concerns or symptoms you are worried about.

Once you choose a date and time and confirm your booking, the questionnaire appears straight away. Please answer it to the end. After that, send “I have booked” and your name to our official LINE.

4

Tell us the following in the questionnaire and on LINE

Hotel name / hotel check-in date / date and time you arrive in Japan / preferred collection date / dose (mg) / number of months

Please give your preferred receiving date, dose and number of months in the questionnaire, and your hotel name and check-in date on our official LINE. You enter the delivery address yourself on the payment page when you pay. Between your payment and dispatch, the delivery address cannot be changed. Because of the way the payment system works, we have no way to change it either. After dispatch, please use the tracking number we send you and contact Yamato Transport (ヤマト運輸) yourself to request a change of delivery date and delivery location. Yamato Transport's Customer Service Center can be reached on 0570-200-000. If you register with Kuroneko Members (クロネコメンバーズ), which is free, you can also make the change online.

There are two ways to receive your medication

Please choose whichever suits you.

A: Receive it at your hotel

We deliver to the hotel where you are staying.

Please check with your hotel in advance - "Can you accept a refrigerated delivery with paid on delivery?"

🔴 If the parcel arrives before your check-in date, the hotel may refuse it. We always schedule delivery for on or after your check-in date, so please tell us that date. Some hotels decline parcels altogether - if yours does, choose option B or contact us on our official LINE.

Once you receive it, put it in the room fridge. Move it to your own fridge as soon as you get home.

B: Collect it at a Yamato Transport branch

You can pick your package up at a nearby Yamato office. When you pay, enter that office's address directly in the delivery address field on the payment page. Packages are held for 3 days. About a third of offices close on weekends and holidays, so check the opening hours before you book if your delivery spans a weekend. Note that some counters inside or in front of stations are baggage-storage points for travellers and do not hand parcels over. The branches you can collect from are listed under "How to receive your medication".

Held for 3 days. ID is required to collect it.

Bring your passport or other photo ID. Showing the payment confirmation email as well makes it more straightforward.

IF RECEIVING AT YOUR HOTEL, CHECK IN ADVANCE
5

If you want hotel delivery, check with the hotel in advance

Please ask your hotel the following.

"Can you accept a refrigerated delivery with paid on delivery?"

If language is a problem, show the Japanese below to the front desk. Fill in your room number and name where it says 〇〇.

お世話になります。〇〇号室に宿泊しております〇〇と申します。滞在中に、冷蔵(クール便)のお荷物が着払いで届く予定です。フロントでお受け取りいただけますでしょうか。送料の現金をフロントにお預けしておくことは可能でしょうか。難しいようでしたら、お荷物が届いた際にお部屋へご連絡いただければ、私が下りてお支払いいたします。お預かりいただく際は、冷蔵での保管をお願いできますと助かります。どうぞよろしくお願いいたします。

(What it says) I am staying in room 〇〇. A refrigerated cash-on-delivery parcel is due to arrive during my stay - could the front desk accept it for me? May I leave the delivery fee in cash at the front desk? If that is difficult, please call my room when it arrives and I will come down to pay. If possible, please keep it refrigerated.

Showing this screen as it is works fine.

If your hotel declines to accept parcel deliveries, then after dispatch please use the tracking number we send you and contact Yamato Transport (ヤマト運輸) yourself to request a change of delivery date and delivery location. Yamato Transport's Customer Service Center can be reached on 0570-200-000. If you register with Kuroneko Members (クロネコメンバーズ), which is free, you can also make the change online. By either of these routes you can also switch to having your parcel held for you at a Yamato Transport branch (営業所止め).

CONSULTATION, PAYMENT, SHIPPING — POSSIBLE FROM OVERSEAS
6

Consultation with the doctor

The doctor holds the consultation based on your questionnaire. This is fine even while you are overseas. Consultations are conducted through your questionnaire and chat on our official LINE; if you would prefer a video or phone consultation, let us know on LINE. It is conducted in English or through a translation app, so there is no need to worry if you do not speak Japanese.

7

Card payment

After the consultation we email a payment link to the address you registered (and also post the URL on LINE). On the payment page, enter your delivery address and card details and pay for the medication. There is no fee.

Payment is by VISA or Mastercard credit card only (debit cards cannot be used).

Please have a VISA or Mastercard credit card ready. Cards issued outside Japan can be used. JCB, American Express and Diners cards, and debit, check and prepaid cards, cannot be used. Please also check your credit limit and expiry date. If the payment does not go through we cannot ship your medication, so please contact us on our official LINE if that happens.

8

Shipping

We ship by refrigerated courier right after payment.

Your consultation date and delivery date cannot be far apart

We ship all medication together on the day after your consultation, and we cannot accept requests for a specific shipping date. Please book about 5 days before the day you want to receive your medication. Those 5 days are calendar days, including weekends and public holidays. For example, if you want to receive your medication on the 26th of the month, have your consultation around the 21st. If you book later than that, your medication will not arrive in time, and if you book a week or more earlier, we will ask you to book again. Tell us the day you would like to receive your medication in the questionnaire that appears after you book.

AFTER YOU ARRIVE IN JAPAN — RECEIVING YOUR MEDICATION
9

Pay the shipping (you do not need cash)

Shipping is paid on delivery, either to the driver or at the office counter. You do not need cash. If your card supports contactless payment - called Visa Touch in Japan - you simply hold it against the reader. Look for the wave-shaped symbol on your card; cards issued outside Japan work the same way. Suica and other transport IC cards, and QR payments such as PayPay, Rakuten Pay and d-barai, are also accepted. Note that ordinary card payments using a signature or PIN are not accepted - contactless only.

10

Carry it home in a cool bag

Please carry it in a cool bag, and put it in a refrigerator as soon as you get home.

We send a prescription certificate to everyone, free of charge

We send a prescription certificate free of charge to everyone who receives a prescription, without your having to ask for it. It is a document written in both English and Japanese, and you can present it at customs. No request is needed. We send it as a PDF to your registered email address and to our official LINE account.

💬Ask us anything on our official LINE (10:00-19:00)
GET STARTED

Start with a booking。Start Right Now。

Initial fee ¥0・No cancellation fees・No lock-in. Complete via smartphone.

Three things to check before you book
  • Cancelling is free at any time before the consultation. We charge no cancellation or termination fees.
  • The delivery address cannot be changed after payment, and cancellation or refunds after payment are not available as a rule.
  • If we cannot deliver because of incomplete registered details, refrigerated medication is disposed of and the medication cost cannot be refunded.
Read the full cancellation and refund policy
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